With regards to Malaysia, with more than 19,337 cases reported in 2010, TB was notified as the second highest infectious disease after dengue fever in 2010, and remains a major public health challenge. Furthermore, the present rate of decline (2.2% per year) is insufficient to reach the target for the elimination of TB by 2050 in the world, defined as ≤1 TB case per million population per year. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.ĭespite a recently observed decrease in number of Tuberculosis (TB) cases, in 2012 it led to an estimated 8.6 million new cases and 1.3 million death worldwide – including 320,000 deaths among TB/HIV co infected patients. fellowship by the European Social Funds through the Regional Council of Guadeloupe, France. Fazli Ismail was awarded a USM Fellowship by Universiti Sains Malaysia. All relevant data are within the paper and its Supporting Information files.įunding: This study was supported by USM Research University Grant (1001/PPSP/853001). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: The authors confirm that all data underlying the findings are fully available without restriction. Received: JAccepted: NovemPublished: December 11, 2014Ĭopyright: © 2014 Ismail et al.
PLoS ONE 9(12):Įditor: Srinand Sreevatsan, University of Minnesota, United States of America
Citation: Ismail F, Couvin D, Farakhin I, Abdul Rahman Z, Rastogi N, Suraiya S (2014) Study of Mycobacterium tuberculosis Complex Genotypic Diversity in Malaysia Reveals a Predominance of Ancestral East-African-Indian Lineage with a Malaysia-Specific Signature.
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